EGCG Attenuates Uric Acid-Induced Inflammatory and Oxidative Stress Responses by Medicating the NOTCH Pathway

Figure 1

Effect of UA on the expression of IL-6, ICAM-1, MCP-1, and TNF-α and the ROS production in HUVEC. (a) Western blot analysis for IL-6, ICAM-1, MCP-1, and TNF-α in HUVEC after incubation with UA (8 mg/dL). (b) Representative images showing that intracellular ROS production was detected using CellROX Green Reagent. Histogram illustrating ROS production showed a different response compared with UA. .

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