Neuroprotection by Cocktails of Dietary Antioxidants under Conditions of Nerve Growth Factor Deprivation
Neuroprotection by antioxidant molecules against NGF deprivation. MTT assay on neuronal PC12 cells exposed to NGF deprivation for 24 h. Where indicated, cells were preincubated overnight with RSV (a), QRC (b), GTE (c), OLP (d), CRC (e), LYC (f), NAC (g), ALA (h), ALCAR (i), CoQ (j), or Sel (k) at the indicated concentrations followed by NGF deprivation for 24 h in the presence of the antioxidants. Data are the mean ± SEM of three experiments, each performed in triplicate. , , and versus CTR-NGF; , versus No-NGF (ANOVA and Dunnett’s multiple comparisons test).