TY - JOUR A2 - Fadillioglu, Ersin AU - Zalavras, Athanasios AU - Fatouros, Ioannis G. AU - Deli, Chariklia K. AU - Draganidis, Dimitris AU - Theodorou, Anastasios A. AU - Soulas, Dimitrios AU - Koutsioras, Yiannis AU - Koutedakis, Yiannis AU - Jamurtas, Athanasios Z. PY - 2015 DA - 2015/04/06 TI - Age-Related Responses in Circulating Markers of Redox Status in Healthy Adolescents and Adults during the Course of a Training Macrocycle SP - 283921 VL - 2015 AB - Redox status changes during an annual training cycle in young and adult track and field athletes and possible differences between the two age groups were assessed. Forty-six individuals (24 children and 22 adults) were assigned to four groups: trained adolescents, (TAD, N=13), untrained adolescents (UAD, N=11), trained adults (TA, N=12), and untrained adults (UA, N=10). Aerobic capacity and redox status related variables [total antioxidant capacity (TAC), glutathione (GSH), catalase activity, TBARS, protein carbonyls (PC), uric acid, and bilirubin] were assessed at rest and in response to a time-trial bout before training, at mid- and posttraining. TAC, catalase activity, TBARS, PC, uric acid, and bilirubin increased and GSH declined in all groups in response to acute exercise independent of training status and age. Training improved aerobic capacity, TAC, and GSH at rest and in response to exercise. Age affected basal and exercise-induced responses since adults demonstrated a greater TAC and GSH levels at rest and a greater rise of TBARS, protein carbonyls, and TAC and decline of GSH in response to exercise. Catalase activity, uric acid, and bilirubin responses were comparable among groups. These results suggest that acute exercise, age, and training modulate the antioxidant reserves of the body. SN - 1942-0900 UR - https://doi.org/10.1155/2015/283921 DO - 10.1155/2015/283921 JF - Oxidative Medicine and Cellular Longevity PB - Hindawi Publishing Corporation KW - ER -