Chlorpyrifos Induces the Expression of the Epstein-Barr Virus Lytic Cycle Activator BZLF-1 via Reactive Oxygen Species

Figure 4

CPF-induced DNA damage in Raji cells. Raji cells were exposed to different concentrations of CPF. The comet assay was performed to assess the DNA oxidative damage. (a) Representative comet images for 0–200 μM CPF treatment. (b) Exposure to CPF at any concentration with the exception of 50 μM resulted in an obvious dose-dependent increase in the tail inertia. (c) The antioxidant NAC blocked the CPF-induced DNA damage. The results are expressed as the means ± SEM. , , and .

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(b)

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