Nonenzymatic Reactions above Phospholipid Surfaces of Biological Membranes: Reactivity of Phospholipids and Their Oxidation Derivatives

Scheme 2

Transition state of reaction between PE (blue color) and acetaldehyde (red colour), showing the boundary translation invariance property of PE-surface periodic model. Arrows and green shadows indicate the direction and the protons involved in the transfer, dotted lines represent hydrogen bonds, and R corresponds to PE molecules which contain the amine groups.