Efficacy of N-Acetylcysteine, Glutathione, and Ascorbic Acid in Acute Toxicity of Paraoxon to Wistar Rats: Survival Study

Table 2

Mortality [%] after pretreatments of NEAO and co-application of paraoxon and pralidoxime.

Groups (G)	POX DOSE (μmol/rat)	30 min	1 hour	2 hours	3 hours	4 hours	24 hours	48 hours
G1: POX only	1/2	79/92	83/92	88/92	88/92	88/92	88/92	88/92
G2: PAM before POX	1/2	4/42	17/46	17/46	17/50	17/58	17/71	17/75
G3: NAC before POX	1/2	94/96	94/96	100/100	100/100	100/100	100/100	100/100
G4: NAC before (POX + PAM)	1/2	17/71	33/75	38/79	42/79	42/88	50/92	50/92
G5: (POX + PAM)	1/2	8/75	8/79	13/79	17/79	25/79	25/83	29/83
G6: GSH before (POX + PAM)	1/2	67/46	67/67	71/92	75/96	83/90	83/96	88/96
G7: GSH before POX	1/2	92/83	92/92	96/92	100/92	100/96	100/96	100/96
G8: AA before (POX + PAM)	1/2	58/83	63/83	75/88	79/92	96/92	96/92	96/96
G9: AA before POX	1/2	58/75	67/83	75/83	75/83	75/92	83/100	83/100