Efficacy of N-Acetylcysteine, Glutathione, and Ascorbic Acid in Acute Toxicity of Paraoxon to Wistar Rats: Survival Study

Table 3

Cox analysis of the cumulative relative risk (RR) of death for co-administration of compounds, including 95% confidence interval (CI), of animals exposed to the paraoxon (POX) and adjusted for POX dose (high/low).

Groups	RR ± SD	95% CI	Significance
POX only	1	0-0
POX + PAM + NAC	0.66 ± 15	0.42–0.91
POX + NAC	1.04 ± 0.04	0.97–1.12	NS
POX + PAM	0.33 ± 0.03	0.23–0.43
POX + PAM + GSH	0.81 ± 0.13	0.61–1.02
POX + GSH	1.08 ± 0.03	1.03–1.14	NS
POX + PAM + AA	1.30 ± 0.12	1.10–1.49
POX + AA	0.85 ± 0.28	0.00–3.32