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Figure 1: Physiological response to mechanical ventilation following induction of sepsis over time. O2/FiO2 (a), mean arterial pressure (b), and heart rate (c) were measured. values are calculated by repeated-measures ANOVA. Significant differences are highlighted between groups receiving MV on the same day. *The same time point at which the group received MV at the same day after CLP. Data are presented as mean ± SD.