Research Article

Resveratrol Derivative-Rich Melinjo Seed Extract Attenuates Skin Atrophy in Sod1-Deficient Mice

Figure 1

MSE and RSV attenuate skin atrophy in the Sod1−/− mice. (a) Hematoxylin and eosin staining of the back skin of Sod1−/− (KO) and Sod1+/+ (WT) mice treated with the MSE or RSV. MSE and RSV containing diets were administrated for 12 weeks. The thickness of (b) total, (c) epidermis, and (d) dermis of the back skin of the Sod1−/− and Sod1+/+ mice treated with MSE or RSV ( 10–12). The statistical evaluations were performed using the Tukey’s test. These data indicate the mean ± SD; , . The scale bar represents 100 μm.
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