Resveratrol Derivative-Rich Melinjo Seed Extract Attenuates Skin Atrophy in Sod1-Deficient Mice

Figure 3

MSE and RSV decrease oxidative damage and ROS production. (a) 8-isoprostane content in plasma obtained from Sod1^−/− and Sod1^+/+ mice treated with MSE and RSV ( 10–12). (b) The intracellular ROS levels of bone marrow cells of Sod1^−/− and Sod1^+/+ mice were measured using a DCF dye ( 5-6). (c) The relative intracellular ROS level in Sod1^−/− fibroblasts treated with 10 μM RSV for 72 h was measured by a DCF dye (). The statistical evaluations were performed using the Tukey’s test. These data indicate the mean ± SD; , .

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