Research Article

Oxidative Stress in Dilated Cardiomyopathy Caused by MYBPC3 Mutation

Table 1

Clinical patient characteristics.

PatientsSexAgeClinical information

1M31NYHA IV, severe ischemia
2M43Unknown
3M56Right ventricular heart failure, Uhl's syndrome, severe right ventricular dysplasia, tricuspid regurgitation, and thin IVS
4M54Severe nonobstructive hypertrophic cardiomyopathy, homozygous TNNT mutant, and triple bypass
5F47Automatic implantable cardioverter-defibrillator, atrial fibrillation, hypothyroid, sinus rhythm, left ventricular hypertrophy, LVEF 20–30%, NYHAII/III, and fractional shortening 21%
6F57Defibrillator, septal hypertrophy, LVEF 15%, and NYHA III
7F41Automatic implantable cardioverter-defibrillator, dual pacemaker, LVEF 50%, and NYHA IV
8M61Atrial fibrillation, LVEF 30%, and NYHA III/IV
9M32HOCM, IVS = 23 mm, and LVOT pressure gradient = 88 mmHg
10M60HOCM, IVS = 23 mm, and LVOT pressure gradient = 77 mmHg
11F24HOCM, IVS = 24 mm, and LVOT pressure gradient = 81 mmHg
12M33HOCM, IVS = 21 mm, and LVOT pressure gradient = 59 mmHg
13M17HOCM
14M50HOCM

DonorsSexAgeCause of death

1M56Hypoxia (hanged)
2M45Unknown
3M48Intracranial hemorrhage, cardiac arrest 23 minutes
4F42Multiple sclerosis, Guillain Barré syndrome
5F62Hypoxia (hanged)
6F47Poland syndrome, hydrocephalus, cardiac arrested 35 min, and celsior cardioplegia
7M28Poland syndrome, hydrocephalus, cardiac arrested 35 min, and celsior cardioplegia
8M62Middle cerebral artery aneurism and hemorrhage, brain herniation
9F49Unknown
10M40Unknown
11M29Unknown
12M25Unknown
13M33Unknown

HOCM = hypertrophic obstructive cardiomyopathy, IVS = interventricular septum, LVEF = left ventricular ejection fraction, LVOT = left ventricular outflow tract, and NYHA = New York Heart Association class.