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Oxidative Medicine and Cellular Longevity
Volume 2015, Article ID 467471, 9 pages
http://dx.doi.org/10.1155/2015/467471
Research Article

Antioxidative Diet Supplementation Reverses High-Fat Diet-Induced Increases of Cardiovascular Risk Factors in Mice

1Department for Molecular Biomedicine, Center of Research and Advanced Studies (CINVESTAV) of the National Polytechnic Institute (IPN), Zacatenco, 07360 Mexico City, DF, Mexico
2CINVESTAV-IPN Monterrey, 66600 Apodaca, NL, Mexico
3Superior Medical School, IPN, Postgraduate and Research Section, 11340 Mexico City, DF, Mexico

Received 17 December 2014; Revised 15 March 2015; Accepted 16 March 2015

Academic Editor: Eugene A. Kiyatkin

Copyright © 2015 Hilda Vargas-Robles et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. M. A. van Baak, “Nutrition as a link between obesity and cardiovascular disease: how can we stop the obesity epidemic?” Thrombosis and Haemostasis, vol. 110, no. 4, pp. 689–696, 2013. View at Publisher · View at Google Scholar · View at Scopus
  2. M. A. Pereira, T. E. Kottke, C. Jordan, P. J. O'Connor, N. P. Pronk, and R. Carreón, “Preventing and managing cardiometabolic risk: the logic for intervention,” International Journal of Environmental Research and Public Health, vol. 6, no. 10, pp. 2568–2584, 2009. View at Publisher · View at Google Scholar · View at Scopus
  3. M. Kratz, T. Baars, and S. Guyenet, “The relationship between high-fat dairy consumption and obesity, cardiovascular, and metabolic disease,” European Journal of Nutrition, vol. 52, no. 1, pp. 1–24, 2013. View at Publisher · View at Google Scholar · View at Scopus
  4. E. Hopps, D. Noto, G. Caimi, and M. R. Averna, “A novel component of the metabolic syndrome: the oxidative stress,” Nutrition, Metabolism and Cardiovascular Diseases, vol. 20, no. 1, pp. 72–77, 2010. View at Publisher · View at Google Scholar · View at Scopus
  5. O. Galili, D. Versari, K. J. Sattler et al., “Early experimental obesity is associated with coronary endothelial dysfunction and oxidative stress,” American Journal of Physiology—Heart and Circulatory Physiology, vol. 292, no. 2, pp. H904–H911, 2007. View at Publisher · View at Google Scholar · View at Scopus
  6. I. Abete, E. Goyenechea, M. A. Zulet, and J. A. Martínez, “Obesity and metabolic syndrome: potential benefit from specific nutritional components,” Nutrition, Metabolism and Cardiovascular Diseases, vol. 21, supplement 2, pp. B1–B15, 2011. View at Publisher · View at Google Scholar · View at Scopus
  7. A. B. Crujeiras, M. D. Parra, M. C. Rodríguez, B. E. Martínez de Morentin, and J. A. Martínez, “A role for fruit content in energy-restricted diets in improving antioxidant status in obese women during weight loss,” Nutrition, vol. 22, no. 6, pp. 593–599, 2006. View at Publisher · View at Google Scholar · View at Scopus
  8. E. Kesse-Guyot, N. Ahluwalia, C. Lassale, S. Hercberg, L. Fezeu, and D. Lairon, “Adherence to Mediterranean diet reduces the risk of metabolic syndrome: a 6-year prospective study,” Nutrition, Metabolism and Cardiovascular Diseases, vol. 23, no. 7, pp. 677–683, 2013. View at Publisher · View at Google Scholar · View at Scopus
  9. O. Ilkun and S. Boudina, “Cardiac dysfunction and oxidative stress in the metabolic syndrome: An update on antioxidant therapies,” Current Pharmaceutical Design, vol. 19, no. 27, pp. 4806–4817, 2013. View at Publisher · View at Google Scholar · View at Scopus
  10. S. Devaraj, R. Tang, B. Adams-Huet et al., “Effect of high-dose α-tocopherol supplementation on biomarkers of oxidative stress and inflammation and carotid atherosclerosis in patients with coronary artery disease,” The American Journal of Clinical Nutrition, vol. 86, no. 5, pp. 1392–1398, 2007. View at Google Scholar · View at Scopus
  11. J. H. Y. Wu, N. C. Ward, A. P. Indrawan et al., “Effects of α-tocopherol and mixed tocopherol supplementation on markers of oxidative stress and inflammation in type 2 diabetes,” Clinical Chemistry, vol. 53, no. 3, pp. 511–519, 2007. View at Publisher · View at Google Scholar · View at Scopus
  12. M. Wallert, L. Schmölz, F. Galli, M. Birringer, and S. Lorkowski, “Regulatory metabolites of vitamin E and their putative relevance for atherogenesis,” Redox Biology, vol. 2, pp. 495–503, 2014. View at Publisher · View at Google Scholar
  13. M. Meydani, “Vitamin E modulation of cardiovascular disease,” Annals of the New York Academy of Sciences, vol. 1031, pp. 271–279, 2004. View at Publisher · View at Google Scholar · View at Scopus
  14. G. Cao, R. M. Russell, N. Lischner, and R. L. Prior, “Serum antioxidant capacity is increased by consumption of strawberries, spinach, red wine or vitamin C in elderly women,” Journal of Nutrition, vol. 128, no. 12, pp. 2383–2390, 1998. View at Google Scholar · View at Scopus
  15. M. G. Arellano-Mendoza, H. Vargas-Robles, L. del Valle-Mondragon, A. Rios, and B. Escalante, “Prevention of renal injury and endothelial dysfunction by chronic L-arginine and antioxidant treatment,” Renal Failure, vol. 33, no. 1, pp. 47–53, 2011. View at Publisher · View at Google Scholar · View at Scopus
  16. A. M. Gámez-Méndez, H. Vargas-Robles, M. Arellano-Mendoza, E. Cruz-Laguna, A. Rios, and B. Escalante, “Early stage of obesity potentiates nitric oxide reduction during the development of renal failure,” Journal of Nephrology, vol. 27, no. 3, pp. 281–287, 2014. View at Publisher · View at Google Scholar · View at Scopus
  17. M. G. A. Mendoza, C. Castillo-Henkel, R. Medina-Santillan et al., “Kidney damage after renal ablation is worsened in endothelial nitric oxide synthase (-/-) mice and improved by combined administration of L-arginine and antioxidants,” Nephrology, vol. 13, no. 3, pp. 218–227, 2008. View at Publisher · View at Google Scholar · View at Scopus
  18. M. A. Alam, K. Kauter, K. Withers, C. Sernia, and L. Brown, “Chronic l-arginine treatment improves metabolic, cardiovascular and liver complications in diet-induced obesity in rats,” Food & Function, vol. 4, no. 1, pp. 83–91, 2013. View at Publisher · View at Google Scholar · View at Scopus
  19. B. Harwell, “Biochemistry of oxidative stress,” Biochemical Society Transactions, vol. 35, no. 5, pp. 1147–1150, 2007. View at Publisher · View at Google Scholar · View at Scopus
  20. N. Demircan, A. Gürel, F. Armutcu, M. Ünalacak, E. Aktunç, and H. Atmaca, “The evaluation of serum cystatin C, malondialdehyde, and total antioxidant status in patients with metabolic syndrome,” Medical Science Monitor, vol. 14, no. 2, pp. CR97–CR101, 2008. View at Google Scholar · View at Scopus
  21. J. E. Barbato, B. S. Zuckerbraun, M. Overhaus, K. G. Raman, and E. Tzeng, “Nitric oxide modulates vascular inflammation and intimal hyperplasia in insulin resistance and the metabolic syndrome,” The American Journal of Physiology—Heart and Circulatory Physiology, vol. 289, no. 1, pp. H228–H236, 2005. View at Publisher · View at Google Scholar · View at Scopus
  22. N. Abdilla, M. C. Tormo, M. J. Fabia, F. J. Chaves, G. Saez, and J. Redon, “Impact of the components of metabolic syndrome on oxidative stress and enzymatic antioxidant activity in essential hypertension,” Journal of Human Hypertension, vol. 21, no. 1, pp. 68–75, 2007. View at Publisher · View at Google Scholar · View at Scopus
  23. V. O. Palmieri, I. Grattagliano, P. Portincasa, and G. Palasciano, “Systemic oxidative alterations are associated with visceral adiposity and liver steatosis in patients with metabolic syndrome,” Journal of Nutrition, vol. 136, no. 12, pp. 3022–3026, 2006. View at Google Scholar · View at Scopus
  24. Q. Wang, Y. Sun, A. Ma, Y. Li, X. Han, and H. Liang, “Effects of vitamin E on plasma lipid status and oxidative stress in Chinese women with metabolic syndrome,” International Journal for Vitamin and Nutrition Research, vol. 80, no. 3, pp. 178–187, 2010. View at Publisher · View at Google Scholar · View at Scopus
  25. J. Montonen, P. Knekt, R. Järvinen, and A. Reunanen, “Dietary antioxidant intake and risk of type 2 diabetes,” Diabetes Care, vol. 27, no. 2, pp. 362–366, 2004. View at Publisher · View at Google Scholar · View at Scopus
  26. J. A. Beckman, A. B. Goldfine, M. B. Gordon, and M. A. Creager, “Ascorbate restores endothelium-dependent vasodilation impaired by acute hyperglycemia in humans,” Circulation, vol. 103, no. 12, pp. 1618–1623, 2001. View at Publisher · View at Google Scholar · View at Scopus
  27. N. G. Stephens, A. Parsons, P. M. Schofield et al., “Randomised controlled trial of vitamin E in patients with coronary disease: Cambridge Heart Antioxidant Study (CHAOS),” The Lancet, vol. 347, no. 9004, pp. 781–786, 1996. View at Publisher · View at Google Scholar · View at Scopus
  28. C. J. Lavie and J. N. Milani, “Do antioxidant vitamins ameliorate the beneficial effects of exercise training on insulin sensitivity?” Journal of Cardiopulmonary Rehabilitation and Prevention, vol. 31, no. 4, pp. 211–216, 2011. View at Publisher · View at Google Scholar · View at Scopus
  29. M. Meydani, P. Kwan, M. Band et al., “Long-term vitamin E supplementation reduces atherosclerosis and mortality in Ldlr/ mice, but not when fed Western style diet,” Atherosclerosis, vol. 233, no. 1, pp. 196–205, 2014. View at Publisher · View at Google Scholar · View at Scopus
  30. M. S. Farvid, M. Jalali, F. Siassi, and M. Hosseini, “Comparison of the effects of vitamins and/or mineral supplementation on glomerular and tubular dysfunction in type 2 diabetes,” Diabetes Care, vol. 28, no. 10, pp. 2458–2464, 2005. View at Publisher · View at Google Scholar · View at Scopus
  31. D. N. Granger, S. F. Rodrigues, A. Yildirim, and E. Y. Senchenkova, “Microvascular responses to cardiovascular risk factors,” Microcirculation, vol. 17, no. 3, pp. 192–205, 2010. View at Publisher · View at Google Scholar · View at Scopus
  32. J. Lorin, M. Zeller, J.-C. Guilland, Y. Cottin, C. Vergely, and L. Rochette, “Arginine and nitric oxide synthase: regulatory mechanisms and cardiovascular aspects,” Molecular Nutrition and Food Research, vol. 58, no. 1, pp. 101–116, 2014. View at Publisher · View at Google Scholar · View at Scopus
  33. P. N. Chander, O. Gealekman, S. V. Brodsky et al., “Nephropathy in Zucker diabetic fat rat is associated with oxidative and nitrosative stress: prevention by chronic therapy with a peroxynitrite scavenger ebselen,” Journal of the American Society of Nephrology, vol. 15, no. 9, pp. 2391–2403, 2004. View at Publisher · View at Google Scholar · View at Scopus
  34. S. Lorente-Cebrián, A. G. V. Costa, S. Navas-Carretero, M. Zabala, J. A. Martínez, and M. J. Moreno-Aliaga, “Role of omega-3 fatty acids in obesity, metabolic syndrome, and cardiovascular diseases: a review of the evidence,” Journal of Physiology and Biochemistry, vol. 69, no. 3, pp. 633–651, 2013. View at Publisher · View at Google Scholar · View at Scopus
  35. M. Iantorno, U. Campia, N. Di Daniele et al., “Obesity, inflammation and endothelial dysfunction,” Journal of Biological Regulators & Homeostatic Agents, vol. 28, no. 2, pp. 169–176, 2014. View at Google Scholar
  36. G. Singer and D. N. Granger, “Inflammatory responses underlying the microvascular dysfunction associated with obesity and insulin resistance,” Microcirculation, vol. 14, no. 4-5, pp. 375–387, 2007. View at Publisher · View at Google Scholar · View at Scopus
  37. J. F. Ndisang, “Role of heme oxygenase in inflammation, insulin-signalling, diabetes and obesity,” Mediators of Inflammation, vol. 2010, Article ID 359732, 18 pages, 2010. View at Publisher · View at Google Scholar · View at Scopus
  38. A. J. Szalai, M. A. McCrory, D. Xing et al., “Inhibiting C-reactive protein for the treatment of cardiovascular disease: promising evidence from rodent models,” Mediators of Inflammation, vol. 2014, Article ID 353614, 9 pages, 2014. View at Publisher · View at Google Scholar · View at Scopus