Xanthine Oxidase Inhibitor, Allopurinol, Prevented Oxidative Stress, Fibrosis, and Myocardial Damage in Isoproterenol Induced Aged Rats

Table 1

Effect of allopurinol on body weight and organ weight of isoprenaline treated rats.

Parameters	Control	ISO	ISO + allopurinol
Initial body weight	250.50 ± 12.54	275.35 ± 15.69	261.42 ± 15.24
Final body weight	267.40 ± 13.54	272.60 ± 272.60	274.57 ± 13.65
Kidneys wet weight	0.60 ± 0.02	0.66 ± 0.02	0.63 ± 0.01
Heart wet weight	0.24 ± 0.01	0.35 ± 0.01	0.31 ± 0.01
LV wet weight	0.19 ± 0.01	0.28 ± 0.01	0.25 ± 0.01
RV wet weight	0.09 ± 0.01	0.12 ± 0.01	0.12 ± 0.01

Values are presented as mean ± SEM. N = 5–7 in each group or otherwise specified. One-way ANOVA with Bonferroni tests were done as post hoc test. Values are considered significance at .