DNA Damage and Inhibition of Akt Pathway in MCF-7 Cells and Ehrlich Tumor in Mice Treated with 1,4-Naphthoquinones in Combination with Ascorbate

<div>Antitumor actions of juglone, Q7, and Q9 administered in combination with ascorbate against MCF-7 cells and Ehrlich ascites carcinoma in mice. The effects are the result of intercalation and oxidative attack on DNA of tumor cells and inhibition of Akt pathway.</div>

Oxidative Medicine and Cellular Longevity

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Figure 4: DNA Damage and Inhibition of Akt Pathway in MCF-7 Cells and Ehrlich Tumor in Mice Treated with 1,4-Naphthoquinones in Combination with Ascorbate 

Figure 4 | DNA Damage and Inhibition of Akt Pathway in MCF-7 Cells and Ehrlich Tumor in Mice Treated with 1,4-Naphthoquinones in Combination with Ascorbate 