Research Article

DNA Damage and Inhibition of Akt Pathway in MCF-7 Cells and Ehrlich Tumor in Mice Treated with 1,4-Naphthoquinones in Combination with Ascorbate

Table 1

EC50 values obtained by the MTT assay. MCF-7 cells were treated for 24 h with juglone, Q7, or Q9 (5–80 M) with or without ascorbate 1 mM. Data from three independent experiments.

EC50 (M)
JugloneQ7Q9

6141.650
plus ascorbate 1 mM2826.325.4