Renal Oxidative Stress Induced by Long-Term Hyperuricemia Alters Mitochondrial Function and Maintains Systemic Hypertension

Figure 1

Short-term hyperuricemia induced systemic hypertension but not renal oxidative stress and mitochondrial alterations. Three weeks of oxonic acid dosing induced hyperuricemia and systemic hypertension, but not renal oxidative stress neither renal mitochondrial functional abnormalities.