Review Article

NSAIDs and Cardiovascular Diseases: Role of Reactive Oxygen Species

Figure 2

Pathways involved in the development of cardiovascular diseases by NSAIDS. The figure shows the upregulation and downregulation of various pathways by NSAIDs leading to the development of CVD. Mitochondria play a major role in the generation of ROS induced by NSAIDs followed by oxidative stress and finally CVD.