Research Article

Protective Effects of the Flavonoid Chrysin against Methylmercury-Induced Genotoxicity and Alterations of Antioxidant Status, In Vivo

Figure 1

Impact of oral treatment of rats with CR on induction of DNA-damage by MeHg in (a) lymphocytes and (b) hepatocytes. The animals were treated by gavage with different doses of the flavonoid (CR I: 0.1 mg/kg/bw/day; CR II: 1.0 mg/kg/bw/day; and CR III 10 mg/kg/bw/day) in combination with the metal (30 μg/kg/bw/day) over a period of 45 days. Bars indicate means ± SD of results obtained with six animals per group. Stars indicate significant difference from negative control group; hashes indicate significant difference in comparison to the MeHg group (; one-way ANOVA and Dunnett’s test).
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