Allicin reduces the expression/activity of CD68 and MPO. (a) Confocal microscopic analysis of CD68 in the control and experimental animals. The experimental details are described in Materials and Methods. The secondary antibody used in this study was tagged with DyLight 550, and the cells were counterstained with Hoechst. The control animals exhibited lower CD68 expression. DSS treatment increased the expression of CD68 (Dylight 550; red). However, allicin treatment decreased the expression of CD68. (b) Activity of MPO. The MPO activity is presented as mU/mg of protein. The values are expressed as the means ± S.D. In comparison of control versus DSS, DSS versus DSS + allicin. “” denotes a statistically significant difference at , and ns indicates not significant.