OGG1 Involvement in High Glucose-Mediated Enhancement of Bupivacaine-Induced Oxidative DNA Damage in SH-SY5Y Cells

Figure 1

The effect of glucose on the OGG1 expression as detected by qRT-PCR (a, b) and western blot (c). (a) The OGG1 mRNA level in SH-SY5Y cells serum starved for 24 h, followed by incubation with increasing glucose concentrations (25, 50, and 100 mM) for 2 d. (b) The OGG1 mRNA level in SH-SY5Y cells serum starved for 24 h, followed by incubation with increasing glucose concentrations (25, 50, and 100 mM) for 8 d. (c) The OGG1 protein expression in SH-SY5Y cells serum starved for 24 h, followed by incubation with glucose concentration 50 mM for 2, 4, or 8 d. Data are presented as mean ± SD (). Compared with the group Con, .

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