Myostatin Activates the Ubiquitin-Proteasome and Autophagy-Lysosome Systems Contributing to Muscle Wasting in Chronic Kidney Disease

Table 2

Body weight, TA, Gastroc, and Sol muscle weight data.

	Sham	CKD
Body weight (g)	604.8 ± 21.5	590.9 ± 11.8^**
Gastroc MWW (mg)	2900.9 ± 105.3	2389.8 ± 89.5^**
Sol MWW (mg)	578.9 ± 32.1	403.7 ± 35.1^**
TA MWW (mg)	982.3 ± 53.5	767.8 ± 56.4^**
TA MDW (mg)	276.0 ± 11.0	212.2 ± 15.4^**
TA MDW/BW (mg/g^−1)	0.46 ± 0.02	0.38 ± 0.05^*

TA: tibialis anterior; Gastroc: gastrocnemius; Sol: soleus; MWW: muscle wet weight; MDW: muscle dry weight; BW: body weight. Body weight, muscle wet weight, muscle dry weight, and MDW/BW were evaluated in CKD versus sham-operated control rat. ( and versus sham).