Dry Olive Leaf Extract Counteracts L-Thyroxine-Induced Genotoxicity in Human Peripheral Blood Leukocytes In Vitro

Table 1

Pretreatment protocol: number of cells with damaged DNA from six different subjects, pretreated with different concentrations of dry olive leaf extract (DOLE) and subsequently exposed to oxidants (thyroxine and H₂O₂).

Oxidants		DOLE concentrations
		1 mg/mL	0.5 mg/mL	0.125 mg/mL
Thyroxine; (50 M)	16.67 ± 1.54	3.58 ± 1.0	4.42 ± 1.1	4.25 ± 1.0
H2O2 (25 M)	84.5 ± 4.93	20 ± 7.6	9.83 ± 1.7	8.5 ± 1.9

Values are expressed as mean ± SEM for comet scores in 100 cells from 6 subjects.
< 0.05 DOLE treatment versus oxidant, analyzed by one-way ANOVA test of variance.