Schisandrae Fructus Supplementation Ameliorates Sciatic Neurectomy-Induced Muscle Atrophy in Mice

Figure 1

Effects of EESF supplementation on body weight changes in mice with NTX-induced muscle atrophy. Body weights of each mouse were measured from the day of NTX to sacrifice as described in Section 2. Values are expressed as mean ± S.D. of 10 mice (EESF, Schisandrae Fructus ethanol extract; NTX, Sciatic neurectomy). Day −1 means 1 day before the start of administration, at 13 days after NTX surgery. Zero means at the start of administration, at 14 days after NTX. Twenty-eight means 28 days after the start of administration, at sacrifice. All animals were fasted overnight before NTX, first administration, and sacrifice (arrows). as compared with NTX control mice by the LSD test.