Schisandrae Fructus Supplementation Ameliorates Sciatic Neurectomy-Induced Muscle Atrophy in Mice
Table 4
Changes in the calf thickness in mice with NTX-induced muscle atrophy.
Groups
Calf thicknesses (mm)
Changes after the test article treatment period (mm) []
At NTX
At 14 days after NTX, first administration []
Sacrifice []
Controls
Sham
2.70 ± 0.07
2.85 ± 0.10
3.25 ± 0.12
0.40 ± 0.12
NTX
2.69 ± 0.09
2.22 ± 0.06c
2.03 ± 0.11a
−0.19 ± 0.11a
Reference
Oxymetholone
2.70 ± 0.08
2.22 ± 0.07c
2.45 ± 0.10ab
0.23 ± 0.11ab
EESF treated
500 mg/kg
2.69 ± 0.05
2.23 ± 0.04c
2.44 ± 0.12ab
0.21 ± 0.10ab
250 mg/kg
2.69 ± 0.07
2.22 ± 0.04c
2.33 ± 0.07ab
0.11 ± 0.06ab
125 mg/kg
2.69 ± 0.06
2.22 ± 0.04c
2.30 ± 0.06ab
0.08 ± 0.06ab
Values are expressed as mean ± S.D. of 10 mice. a as compared with sham control mice by the LSD test. b as compared with NTX control mice by the LSD test. c as compared with sham control mice by the MW test.