Schisandrae Fructus Supplementation Ameliorates Sciatic Neurectomy-Induced Muscle Atrophy in Mice

Table 6

Changes in the gastrocnemius muscle antioxidant defense systems in mice with NTX-induced muscle atrophy.

Groups	Fundus antioxidant defense systems
	MDA; (nM/mg protein)	ROS; (RFU/μg protein)	GSH; (nM/mg protein)	SOD; (nM/mim/mg protein)	CAT; (U/mg protein)
Controls
Sham	1.51 ± 0.41	22.86 ± 5.81	0.67 ± 0.14	24.30 ± 6.15	5.13 ± 1.40
NTX	8.66 ± 1.88^c	67.11 ± 12.25^a	0.24 ± 0.07^a	9.61 ± 1.46^c	1.45 ± 0.57^c
Reference
Oxymetholone	4.11 ± 1.22^cd	43.08 ± 10.28^ab	0.45 ± 0.12^ab	18.13 ± 3.66^cd	2.63 ± 0.56^cd
EESF treated
500 mg/kg	4.38 ± 0.90^cd	42.35 ± 9.48^ab	0.49 ± 0.09^ab	18.11 ± 2.36^cd	2.66 ± 0.69^cd
250 mg/kg	5.21 ± 1.17^cd	49.73 ± 11.92^ab	0.42 ± 0.08^ab	15.70 ± 4.05^cd	2.38 ± 0.62^cd
125 mg/kg	6.39 ± 0.83^cd	52.89 ± 11.30^ab	0.37 ± 0.07^ab	14.21 ± 1.97^cd	2.06 ± 0.40^ce

Values are expressed as mean ± S.D. of 10 mice.
^a as compared with sham control mice by the LSD test.
^b as compared with NTX control mice by the LSD test.
^c as compared with sham control mice by the MW test.
^d and ^e as compared with NTX control mice by the MW test.