Schisandrae Fructus Supplementation Ameliorates Sciatic Neurectomy-Induced Muscle Atrophy in Mice
Table 9
Changes in the gastrocnemius muscle histomorphometrical analysis in mice with NTX-induced muscle atrophy.
Groups
Histomorphometry of the gastrocnemius muscle bundles
Mean muscle fiber diameter (μm/fiber)
Number of infiltrated inflammatory cells (cells/mm2)
Regions occupied by collagen fibers (%/mm2)
Controls
Sham
53.23 ± 7.21
5.90 ± 1.52
5.98 ± 3.06
NTX
14.81 ± 3.14a
327.10 ± 96.04a
40.11 ± 6.34a
Reference
Oxymetholone
29.64 ± 2.30ab
86.60 ± 41.21ab
23.04 ± 2.66ab
EESF treated
500 mg/kg
29.94 ± 3.02ab
89.00 ± 22.67ab
23.50 ± 4.11ab
250 mg/kg
29.90 ± 3.74ab
124.00 ± 15.61ab
27.50 ± 5.30ab
125 mg/kg
24.34 ± 4.23ab
148.10 ± 31.97ab
31.34 ± 6.01ab
Values are expressed as mean ± S.D. of 10 mice. a as compared with sham control mice by the MW test. b as compared with NTX control mice by the MW test.