Schisandrae Fructus Supplementation Ameliorates Sciatic Neurectomy-Induced Muscle Atrophy in Mice

Table 9

Changes in the gastrocnemius muscle histomorphometrical analysis in mice with NTX-induced muscle atrophy.

Groups	Histomorphometry of the gastrocnemius muscle bundles
	Mean muscle fiber diameter (μm/fiber)	Number of infiltrated inflammatory cells (cells/mm^2)	Regions occupied by collagen fibers (%/mm^2)
Controls
Sham	53.23 ± 7.21	5.90 ± 1.52	5.98 ± 3.06
NTX	14.81 ± 3.14^a	327.10 ± 96.04^a	40.11 ± 6.34^a
Reference
Oxymetholone	29.64 ± 2.30^ab	86.60 ± 41.21^ab	23.04 ± 2.66^ab
EESF treated
500 mg/kg	29.94 ± 3.02^ab	89.00 ± 22.67^ab	23.50 ± 4.11^ab
250 mg/kg	29.90 ± 3.74^ab	124.00 ± 15.61^ab	27.50 ± 5.30^ab
125 mg/kg	24.34 ± 4.23^ab	148.10 ± 31.97^ab	31.34 ± 6.01^ab

Values are expressed as mean ± S.D. of 10 mice.
^a as compared with sham control mice by the MW test.
^b as compared with NTX control mice by the MW test.