Protective Pleiotropic Effect of Flavonoids on NAD⁺ Levels in Endothelial Cells Exposed to High Glucose

Figure 3

(a) Kinetics of porcine aldose reductase in the absence and presence of flavonoids. Data are expressed as mean ± standard deviation of at least three separate experiments. compared to control. (b) An example of a Michaelis Menten plot of aldose reductase in absence (filled circles) and presence of 5 μM quercetin (filled squares), 5 μM rutin (open triangles), 5 μM flavone (filled triangles), or 0.5 μM sorbinil (open circles). Data are expressed as mean ± standard error of at least three experiments.

(a)

(b)