Table of Contents Author Guidelines Submit a Manuscript
Oxidative Medicine and Cellular Longevity
Volume 2015, Article ID 906787, 8 pages
http://dx.doi.org/10.1155/2015/906787
Research Article

Allopurinol Protects against Ischemia/Reperfusion-Induced Injury in Rat Urinary Bladders

1Department of Urology, School of Medicine, Chungnam National University Hospital, Daejeon 301-721, Republic of Korea
2Department of Surgery, School of Medicine, Chungnam National University Hospital, Daejeon 301-721, Republic of Korea
3Division of Bioconvergence Analysis, Korea Basic Science Institute (KBSI), Daejeon 305-333, Republic of Korea
4Department of Functional Genomics, University of Science and Technology (UST), Daejeon 305-806, Republic of Korea

Received 18 December 2014; Revised 27 February 2015; Accepted 19 March 2015

Academic Editor: Aldrin V. Gomes

Copyright © 2015 Ju-Hyun Shin et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. G.-M. Pinggera, M. Mitterberger, E. Steiner et al., “Association of lower urinary tract symptoms and chronic ischaemia of the lower urinary tract in elderly women and men: assessment using colour Doppler ultrasonography,” BJU International, vol. 102, no. 4, pp. 470–474, 2008. View at Publisher · View at Google Scholar · View at Scopus
  2. R. T. Kershen, K. M. Azadzoi, and M. B. Siroky, “Blood flow, pressure and compliance in the male human bladder,” Journal of Urology, vol. 168, no. 1, pp. 121–125, 2002. View at Publisher · View at Google Scholar · View at Scopus
  3. K. M. Azadzoi, T. Tarcan, M. B. Siroky, and R. J. Krane, “Atherosclerosis-induced chronic ischemia causes bladder fibrosis and non-compliance in the rabbit,” Journal of Urology, vol. 161, no. 5, pp. 1626–1635, 1999. View at Publisher · View at Google Scholar · View at Scopus
  4. M. Nomiya, O. Yamaguchi, K.-E. Andersson et al., “The effect of atherosclerosis-induced chronic bladder ischemia on bladder function in the rat,” Neurourology and Urodynamics, vol. 31, no. 1, pp. 195–200, 2012. View at Publisher · View at Google Scholar · View at Scopus
  5. D. L. Maass, J. White, and J. W. Horton, “IL-1β and IL-6 act synergistically with TNF-α to alter cardiac contractile function after burn trauma,” Shock, vol. 18, no. 4, pp. 360–366, 2002. View at Publisher · View at Google Scholar · View at Scopus
  6. J. M. McCord, “Oxygen-derived free radicals in postischemic tissue injury,” The New England Journal of Medicine, vol. 312, no. 3, pp. 159–163, 1985. View at Publisher · View at Google Scholar · View at Scopus
  7. M. Oka, T. Fukui, M. Ueda, M. Tagaya, T. Oyama, and M. Tanaka, “Suppression of bladder oxidative stress and inflammation by a phytotherapeutic agent in a rat model of partial bladder outlet obstruction,” The Journal of Urology, vol. 182, no. 1, pp. 382–390, 2009. View at Publisher · View at Google Scholar · View at Scopus
  8. S. Shimizu, M. Saito, Y. Kinoshita et al., “Acute urinary retention and subsequent catheterization cause lipid peroxidation and oxidative DNA damage in the bladder: preventive effect of edaravone, a free-radical scavenger,” BJU International, vol. 104, no. 5, pp. 713–717, 2009. View at Publisher · View at Google Scholar · View at Scopus
  9. V. Agarwal, N. Hans, and F. H. Messerli, “Effect of allopurinol on blood pressure: a systematic review and meta-analysis,” Journal of Clinical Hypertension, vol. 15, no. 6, pp. 435–442, 2013. View at Publisher · View at Google Scholar · View at Scopus
  10. F. D. Rachmat, J. Rachmat, S. Sastroasmoro, and S. I. Wanandi, “Effect of allopurinol on oxidative stress and hypoxic adaptation response during surgical correction of tetralogy of fallot,” Acta Medica Indonesiana, vol. 45, no. 2, pp. 94–100, 2013. View at Google Scholar
  11. A. H. Ragab, E. Gilkerson, and M. Myers, “The effect of 6-mercaptopurine and allopurinol on granulopoiesis,” Cancer Research, vol. 34, no. 9, pp. 2246–2249, 1974. View at Google Scholar · View at Scopus
  12. W.-Y. Lee, E.-J. Koh, and S.-M. Lee, “A combination of ischemic preconditioning and allopurinol protects against ischemic injury through a nitric oxide-dependent mechanism,” Nitric Oxide, vol. 26, no. 1, pp. 1–8, 2012. View at Publisher · View at Google Scholar · View at Scopus
  13. G. Bratslavsky, B. A. Kogan, S. Matsumoto, A. R. Aslan, and R. M. Levin, “Reperfusion injury of the rat bladder is worse than ischemia,” The Journal of Urology, vol. 170, no. 5, pp. 2086–2090, 2003. View at Publisher · View at Google Scholar · View at Scopus
  14. J.-H. Shin, G.-H. Kim, K.-H. Song, Y.-G. Na, C.-K. Sul, and J.-S. Lim, “Protective effect of N-acetylcysteine against ischemia/reperfusion injury in rat urinary bladders,” Cell Biochemistry and Function, vol. 32, no. 1, pp. 24–30, 2014. View at Publisher · View at Google Scholar · View at Scopus
  15. X. Yu, E. Patterson, S. Huang, M. W. Garrett, and D. C. Kem, “Tumor necrosis factor α, rapid ventricular tachyarrhythmias, and infarct size in canine models of myocardial infarction,” Journal of Cardiovascular Pharmacology, vol. 45, no. 2, pp. 153–159, 2005. View at Publisher · View at Google Scholar · View at Scopus
  16. T. Ardan, J. Kovačeva, and J. Čejková, “Comparative histochemical and immunohistochemical study on xanthine oxidoreductase/xanthine oxidase in mammalian corneal epithelium,” Acta Histochemica, vol. 106, no. 1, pp. 69–75, 2004. View at Publisher · View at Google Scholar · View at Scopus
  17. C. E. Berry and J. M. Hare, “Xanthine oxidoreductase and cardiovascular disease: molecular mechanisms and pathophysiological implications,” The Journal of Physiology, vol. 555, no. 3, pp. 589–606, 2004. View at Publisher · View at Google Scholar · View at Scopus
  18. J. B. Derks, M. A. Oudijk, H. L. Torrance et al., “Allopurinol reduces oxidative stress in the ovine fetal cardiovascular system after repeated episodes of ischemia-reperfusion,” Pediatric Research, vol. 68, no. 5, pp. 374–380, 2010. View at Publisher · View at Google Scholar · View at Scopus
  19. P.-G. Liu, S.-Q. He, Y.-H. Zhang, and J. Wu, “Protective effects of apocynin and allopurinol on ischemia/reperfusion-induced liver injury in mice,” World Journal of Gastroenterology, vol. 14, no. 18, pp. 2832–2837, 2008. View at Publisher · View at Google Scholar · View at Scopus
  20. D. R. Meldrum, “Tumor necrosis factor in the heart,” The American Journal of Physiology—Regulatory Integrative and Comparative Physiology, vol. 274, no. 3, part 2, pp. R577–R595, 1998. View at Google Scholar · View at Scopus
  21. X. Gao, H. Zhang, S. Belmadani et al., “Role of TNF-α-induced reactive oxygen species in endothelial dysfunction during reperfusion injury,” The American Journal of Physiology—Heart and Circulatory Physiology, vol. 295, no. 6, pp. H2242–H2249, 2008. View at Publisher · View at Google Scholar · View at Scopus
  22. L. Zhao, D.-Q. Peng, J. Zhang et al., “Extracellular signal-regulated kinase 1/2 activation is involved in intermedin1-53 attenuating myocardial oxidative stress injury induced by ischemia/reperfusion,” Peptides, vol. 33, no. 2, pp. 329–335, 2012. View at Publisher · View at Google Scholar · View at Scopus
  23. T. Yin, G. Sandhu, C. D. Wolfgang et al., “Tissue-specific pattern of stress kinase activation in ischemic/reperfused heart and kidney,” The Journal of Biological Chemistry, vol. 272, no. 32, pp. 19943–19950, 1997. View at Publisher · View at Google Scholar · View at Scopus
  24. Y. K. Verma, P. K. Raghav, H. G. Raj, R. P. Tripathi, and G. U. Gangenahalli, “Enhanced heterodimerization of Bax by Bcl-2 mutants improves irradiated cell survival,” Apoptosis, vol. 18, no. 2, pp. 212–225, 2013. View at Publisher · View at Google Scholar · View at Scopus
  25. Z.-Y. Hu and J. Liu, “Effects of emulsified isoflurane on haemodynamics and cardiomyocyte apoptosis in rats with myocardial ischaemia,” Clinical and Experimental Pharmacology and Physiology, vol. 36, no. 8, pp. 776–783, 2009. View at Publisher · View at Google Scholar · View at Scopus
  26. C. R. Weston, K. Balmanno, C. Chalmers et al., “Activation of ERK1/2 by deltaRaf-1:ER represses Bim expression independently of the JNK or PI3K pathways,” Oncogene, vol. 22, no. 9, pp. 1281–1293, 2003. View at Publisher · View at Google Scholar · View at Scopus