Review Article

Anticancer Properties of Phyllanthus emblica (Indian Gooseberry)

Table 1

Molecules from Phyllanthus emblica fruit extract having proven anticancer properties.

Phenolic compounds from Phyllanthus emblica extract identified by HPLC having anticancer propertiesCancer model utilized to identify antiproliferative and antitumor properties

Ellagic acid (tannin)Colon, prostate cell lines, and breast and prostate xenografts

Corilagin (tannin)Ovarian cancer cells, liver cancer cells, and hepatocarcinoma xenografts

Pyrogallol (tannin)Lung cancer cells, gastric cancer cells, and lung adenocarcinoma xenografts

Chebulagic acid (tannin)Retinoblastoma colon cancer, breast cancer, prostate cancer, and leukemia cancer cell lines

Gallic acid (tannin)Breast and lung cancer cell lines, some activity against lung cancer xenograft

Quercetin (flavonoid)Numerous cancer cell lines from multiple tissue types, transgenic murine model of breast cancer, leukemia xenograft, and phase I clinical trial