Research Article

Flaxseed Oil Containing α-Linolenic Acid Ester of Plant Sterol Improved Atherosclerosis in ApoE Deficient Mice

Figure 2

Treatment of FO+ALA-PS prevents atherosclerotic development via anti-inflammatory and antiproliferative actions. Representative images of aortic cross-sections immunostained with markers of macrophage infiltration, inflammation, and proliferation from mice fed a normal, HFD, FO, or ALA-PS diet for 18 wk. Immunoreactivity to MAC (a), Ly-6C (b), and SMC (c) antibodies are evident with brownish diaminobenzidine staining (magnification ×400).
(a)
(b)
(c)