Research Article
Partial Oxygen Pressure Affects the Expression of Prognostic Biomarkers HIF-1 Alpha, Ki67, and CK20 in the Microenvironment of Colorectal Cancer Tissue
Figure 7
Low pO2 affects the activity of biomarkers of CRC. Low pO2 affects the activity of biomarkers of CRC via affecting ROS-mediated multiple pathways or CK20 pathway. The effects of these biomarkers lead to poor differentiation, cell proliferation, and angiogenesis.