Research Article

Chronic Alcohol Intoxication and Cortical Ischemia: Study of Their Comorbidity and the Protective Effects of Minocycline

Figure 5

Chronic alcohol intoxication (CAI) reduces minocycline- (Minc-) induced protection in behavioral alterations and oxidative stress caused by ischemia (stroke). (a) Open field; (b) rotarod (three sessions at 15 rpm); (c) nitrite concentration; (d) lipid peroxidation (malonaldehyde (MDA) concentration). Data: mean ± SEM [ (a, b), (c, d)]. versus all groups; versus control; versus control and stroke/Minc.