Phenolic Composition and Antioxidant and Antiproliferative Activities of the Extracts of Twelve Common Bean (Phaseolus vulgaris L.) Endemic Ecotypes of Southern Italy before and after Cooking

Table 5

The antiproliferative activity of the extracts on MCF-7, A549, and Caco-2 cells. EC50 values indicate the concentration (expressed as μg equivalent of gallic acid of total polyphenols/mL) able to reduce cell viability by 50% (±SD).

Sample	MCF-7 cell line; EC50; μg GAE mL^−1; (±SD)	CaCo-2 cell line; EC50; μg GAE mL^−1; (±SD)	A549 cell line; EC50; μg GAE mL^−1; (±SD)
CR	29.40 (1.13)	28.52 (4.9)	31.32 (4.2)
CRc	44.17 (2.7)	37.49 (6.37)	68.79 (0.61)
OR	128.17 (1.17)	58.05 (4.16)	130.83 (2.92)
Orc	135.81 (0.54)	77.62 (2.23)	121.09 (2.84)
Z	185.44 (2.04)	49.85 (6.01)	177.96 (0.61)
Zc	196.70 (1.7)	66.29 (3.11)	273.08 (4.69)
P	333.37 (2.3)	186.18 (14.11)	377.40 (8.34)
Pc	115.33 (1.6)	72.23 (8.72)	252.81 (2.28)
S	165.57 (0.52)	100.17 (2.36)	293.62 (6.75)
Sc	181.36 (0.47)	55.65 (2.9)	213.27 (7.16)
Si	102.60 (0.84)	44.46 (3.73)	122.43 (1.5)
Sic	158.61 (2.7)	76.50 (2.39)	88.01 (1.15)
NA	67.64 (1.06)	53.75 (1.47)	49.40 (0.55)
NAc	82.57 (0.11)	55.46 (2.02)	55.80 (1.26)
NF	63.75 (1.3)	35.79 (4.39)	54.0 (5.51)
NFc	33.6 (1.27)	29.4 (3.96)	31.92 (3.08)
NC	119.02 (1.69)	73.53 (2.36)	118.35 (1.63)
NCc	107.16 (1.03)	52.97 (1.87)	49.486 (2.56)