Oxidative Medicine and Cellular Longevity / 2016 / Article / Fig 7

Research Article

Berberine Attenuates Myocardial Ischemia/Reperfusion Injury by Reducing Oxidative Stress and Inflammation Response: Role of Silent Information Regulator 1

Figure 7

Effects of berberine and sirtinol treatment on inflammation response in normal rat heart. Normal SD rats were exposed to BBR treatment (200 mg/kg/d for 2 weeks) in the absence or presence of sirtinol (Stnl, 2 mg/kg/d for 1 week) and then subjected to myocardial ischemia reperfusion (MI/R) operation. Cardiac oxidative stress level was measured after 6 hr of reperfusion. (a) Myocardium IL-6 level. (b) Myocardium TNF-α level. (c) Serum TNF-α level. (d) Myocardium MPO activity. The results are expressed as the mean ± SEM, /group. versus Sham group, versus MI/R + V group, and versus MI/R + BBR group.

We are committed to sharing findings related to COVID-19 as quickly as possible. We will be providing unlimited waivers of publication charges for accepted research articles as well as case reports and case series related to COVID-19. Review articles are excluded from this waiver policy. Sign up here as a reviewer to help fast-track new submissions.