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Oxidative Medicine and Cellular Longevity
Volume 2016 (2016), Article ID 1874762, 13 pages
http://dx.doi.org/10.1155/2016/1874762
Research Article

Protective Effects of Carvedilol and Vitamin C against Azithromycin-Induced Cardiotoxicity in Rats via Decreasing ROS, IL1-β, and TNF-α Production and Inhibiting NF-κB and Caspase-3 Expression

1Department of Pharmacology and Toxicology, Faculty of Pharmacy, King Abdulaziz University, Elkandarh, Jeddah 21589, Saudi Arabia
2Department of Pharmacology and Toxicology, Faculty of Pharmacy, Tanta University, Tanta, Egypt
3Department of Pathology, Faculty of Medicine, Tanta University, Tanta, Egypt

Received 26 December 2015; Revised 27 March 2016; Accepted 12 April 2016

Academic Editor: Antonio Ayala

Copyright © 2016 Nagla A. El-Shitany and Karema El-Desoky. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

How to Cite this Article

Nagla A. El-Shitany and Karema El-Desoky, “Protective Effects of Carvedilol and Vitamin C against Azithromycin-Induced Cardiotoxicity in Rats via Decreasing ROS, IL1-β, and TNF-α Production and Inhibiting NF-κB and Caspase-3 Expression,” Oxidative Medicine and Cellular Longevity, vol. 2016, Article ID 1874762, 13 pages, 2016. doi:10.1155/2016/1874762