Protective Effects of Carvedilol and Vitamin C against Azithromycin-Induced Cardiotoxicity in Rats via Decreasing ROS, IL1-β, and TNF-α Production and Inhibiting NF-κB and Caspase-3 Expression

Table 2

Effect of carvedilol and vitamin C on plasma lactate dehydrogenase (LDH) and creatine phosphokinase (CPK) enzyme activity measured in azithromycin-treated rats.

Groups	LDH (U/L)	CPK (U/L)
Control	181 ± 77	62 ± 17
Azithromycin	417 ± 84	225 ± 61
Carvedilol + azithromycin	156 ± 109	197 ± 75
Vitamin C + azithromycin	195 ± 125	97 ± 32

Data are presented as mean ± SDM ().
Significant versus control (p ≤ 0.05).
Significant versus azithromycin (p ≤ 0.05).