Acute Exercise-Induced Mitochondrial Stress Triggers an Inflammatory Response in the Myocardium via NLRP3 Inflammasome Activation with Mitophagy

Figure 4

To investigate the mitochondrial oxidative stress response in the myocardium, ROS generation rate, MnSOD activity, and MDA content were measured. Compared with that of the RC group, mitochondrial ROS generation and MDA content were both increased during acute exercise and early recovery ((a) and (b)), but MnSOD activity was not increased until late recovery (c). Each bar represents the mean ± SEM of a treatment group (). and versus RC group.

(a)

(b)

(c)