Hydrogen Sulfide Protects against Chronic Unpredictable Mild Stress-Induced Oxidative Stress in Hippocampus by Upregulation of BDNF-TrkB Pathway

Figure 1

Effect of H₂S on the generations of MDA and 4-HNE in the hippocampus of CUMS-exposed rats. Rats were exposed to CUMS for 2 w and then cotreated with NaHS (0.03 or 0.1 mmol/kg/day, i.p.) and CUMS for 2 w. The levels of MDA (a) and 4-HNE (b) in the hippocampus of rats were detected by ELISA kit. Values are expressed as mean ± SEM (–5/group). , versus the control group; , , versus the CUMS- treated group.

(a)

(b)