Advanced Glycation End Products Evolution after Pancreas-Kidney Transplantation: Plasmatic and Cutaneous Assessments

Table 2

Patients’ graft function and lipid profile evolution during the first year.

Pts	Creat; T3	Creat; T6	Creat; T12	GFR; T3	GFR; T6	GFR; T12	Gluc; T0	Gluc; T3	Gluc; T6	Gluc; T12	HbA1c; T0	HbA1c; T3	HbA1c; T6	HbA1c; T12	Chol; T0	Chol; T3	Chol; T6	Chol; T12	TG; T0	TG; T3	TG; T6	TG; T12	LDL-c; T12	HDL-c; T12	CRP; T12
n = 1	0.95	1.00	1.17	71	67	64	469	78	72	75	10/85.8	5.5/36.6	5.3/34.4	5.1/32.2	136	212	158	170	229	84	130	91	95	55	1.4
n = 2	1.33	1.24	1.18	65	69	72	268	78	89	81	6.8/50.8	5.6/37.7	5.4/35.5	5.4/35.5	161	141	156	176	100	91	81	67	86	75	1.6
n = 3	0.92	0.85	0.96	103	107	104	246	76	82	79	7.4/57.4	5.4/35.5	5.2/33.3	4.9/30.1	186	110	112	147	203	78	82	59	84	61	1.2
n = 4	1.40	1.35	1.45	59	61	58	169	87	85	85	6.5/47.5	5.3/34.4	5.2/33.3	5.1/32.2	97	126	151	122	77	108	83	98	58	57	2.6
n = 5	1.05	1.02	0.93	88	91	95	315	91	90	88	8.5/69.4	5.4/35.5	5.3/34.4	5.1/32.2	80	101	113	97	96	39	27	20	16	67	3.3
n = 6	1.09	1.04	1.02	64	67	68	345	72	84	79	11/96.7	5.3/34.4	5.6/37.7	5.3/34.4	230	226	212	207	155	99	76	84	115	58	2.1
n = 7	0.75	0.81	0.85	88	85	83	217	69	71	64	9.8/83.6	6.1/43.2	5.5/36.6	5.5/36.6	168	147	139	155	151	127	88	59	70	70	1
n = 8	1.27	1.05	1.30	58	66	57	482	88	77	90	7.3/56.3	5.8/39.9	6.0/42.1	5.9/41.0	190	188	177	158	140	78	98	76	79	64	2.5
n = 9	1.13	0.95	0.93	59	71	74	110	86	82	81	6.7/49.7	5.4/35.5	5.2/33.3	5.2/33.3	192	213	271	192	263	255	245	158	120	40	1.2
n = 10	0.84	1.01	0.90	89	76	87	162	79	81	73	10/85.8	4.9/30.1	5.4/35.5	5.3/34.4	139	183	202	172	191	229	146	96	86	76	1.3
n = 11	0.91	1.01	0.95	81	72	77	189	77	71	88	8.2/66.1	5.6/37.7	5.1/32.2	5.2/33.3	171	176	183	181	141	106	89	65	111	65	0.7
n = 12	0.75	0.80	0.65	91	88	110	277	90	86	84	6.1/43.2	6.0/42.1	5.7/38.8	5.4/35.5	146	215	193	188	104	118	97	72	99	67	1.5
n = 13	1.90	1.80	1.36	36	39	51	523	100	104	96	7.2/55.2	6.3/45.4	6.2/44.3	5.9/41.0	190	188	185	189	322	265	131	136	94	57	0.9
n = 14	1.37	1.39	1.29	66	65	70	116	83	80	69	8.0/63.9	5.4/35.5	5.2/33.3	5.0/31.1	195	186	179	160	106	107	99	69	71	79	0.7
n = 15	1.27	1.24	1.20	70	73	76	487	91	93	92	9.3/78.1	6.2/44.3	5.9/41.0	5.7/38.8	171	117	122	148	100	96	92	87	76	55	0.7
n = 16	1.38	1.30	1.30	64	69	69	405	98	86	87	6.7/49.7	6.4/46.4	6.3/45.4	5.8/39.9	152	149	144	137	113	106	95	91	59	60	1.1
n = 17	0.85	0.88	1.09	87	85	82	279	84	75	101	9.7/82.5	6.1/43.2	5.5/36.6	5.6/37.7	181	129	137	139	183	56	62	66	77	52	0.7
n = 18	0.86	1.09	0.99	110	95	97	405	79	100	91	11/96.7	6.4/46.4	6.2/44.3	5.1/32.2	138	188	221	161	79	136	145	149	100	24	1.5
n = 19	0.90	0.89	0.95	79	79	76	212	63	72	75	6.6/48.6	5.2/33.3	5.3/34.4	5.0/31.1	151	225	175	193	107	111	115	74	123	55	0.7
n = 20	1.13	1.25	1.16	84	77	79	398	100	86	88	8.6/70.5	5.7/38.8	5.4/35.5	5.3/34.4	134	202	196	188	134	172	168	156	113	52	4.8
	Mean	Mean	Mean	Mean	Mean	Mean	Mean	Mean	Mean	Mean	Mean	Mean	Mean	Mean	Mean	Mean	Mean	Mean	Mean	Mean	Mean	Mean	Mean	Mean	Mean
	1.10	1.10	1.08	76	75	78	304	83	83	83	8.3/67.2	5.7/38.8	5.6/37.7	5.3/34.4	160	171	171	164	150	123	107	89	87	59	1.6
	SD	SD	SD	SD	SD	SD	SD	SD	SD	SD	SD	SD	SD	SD	SD	SD	SD	SD	SD	SD	SD	SD	SD	SD	SD
	0.29	0.24	0.20	18	14	16	129	10	9	9	1.6/17.5	0.44/4.6	0.38/4.2	0.30/3.3	35	40	40	27	65	62	46	36	25	13	1.0

Creat: serum creatinine (mg/dL); GFR: e-GFR (mL/min/1.73 m², MDRD calculation); Gluc: fasting glucose (mg/dL); HbA1c: glycated hemoglobin (%/mmol/mol); Chol T: total cholesterol (mg/dL); TG: triglycerides (mg/dL); LDL-c: low-density lipoprotein-cholesterol (mg/dL); HDL-c: high-density lipoprotein-cholesterol (mg/dL); CRP: C-reactive protein (mg/L); Pts: patients; SD: standard deviation; T0: time 0; T3: 3 months; T6: 6 months; T12: 12 months.