Research Article

Advanced Glycation End Products Evolution after Pancreas-Kidney Transplantation: Plasmatic and Cutaneous Assessments

Table 3

Skin biopsies: AGE immunoreaction pattern and intensity before and after SPKT.

Case number
(patients)
SPKTEpidermisEpidermisEpidermis
AGE immunoreactionImmunoreaction patternIntensity
(layers with positive immunostain)(peripheral; diffuse; Mixt: both coexist)(from 0 to 3+)

1BeforeBasal, spinous, granular Diffuse cytoplasmic2+ (basal layer 1+)
AfterBasal, spinous, granular Peripheral/interkeratinocytic2+

2BeforeBasal, spinousPeripheral/interkeratinocytic1+
AfterBasalPeripheral/interkeratinocytic1+

3BeforeBasal, spinous, granular Diffuse cytoplasmic2+
AfterBasal, spinous, granular Diffuse cytoplasmic1+

4BeforeBasal, spinous, granular Diffuse cytoplasmic3+
AfterBasal, spinous, granular Peripheral/interkeratinocytic2+

5BeforeBasal, spinous, granular Diffuse cytoplasmic2+
AfterBasal, spinous, granular Peripheral/interkeratinocytic1+/2+ (only spinous layer 2+)

6BeforeBasal, spinous, granular Diffuse cytoplasmic2+
AfterBasal, spinous, granular Mixt1+/2+

7BeforeBasal, spinous, granular Diffuse cytoplasmic2+
AfterBasal, spinous, granular Mixt1+/2+

8BeforeBasal, spinous, granular Diffuse cytoplasmic3+
AfterBasal, spinous, granular Peripheral/interkeratinocytic1+

9BeforeBasal, spinous, granular Mixt1+
AfterBasalPeripheral/interkeratinocytic0/1+ (only basal layer 1+)

10BeforeBasal, spinous, granular Diffuse cytoplasmic2+
AfterBasalPeripheral/interkeratinocytic1+

11BeforeBasal, spinous, granular Diffuse cytoplasmic2+
AfterBasal, spinous, granular Peripheral/interkeratinocytic2+

12BeforeNoneā€‰0
AfterNoneā€‰0

13BeforeBasal, spinous, granular Diffuse cytoplasmic2+
AfterBasal, spinous, granular Peripheral/interkeratinocytic1+

14BeforeBasal, spinous, granular Diffuse cytoplasmic1+
AfterBasal, spinous, granular Peripheral/interkeratinocytic1+

15BeforeBasal, spinous, granular Diffuse cytoplasmic1+
AfterBasal, spinous, granular Peripheral/interkeratinocytic1+