Dietary Phenolic Compounds Interfere with the Fate of Hydrogen Peroxide in Human Adipose Tissue but Do Not Directly Inhibit Primary Amine Oxidase Activity

Figure 8

Docking poses of resveratrol, pterostilbene, quercetin, and caffeic acid in the active sites of human MAO-A, MAO-B, and SSAO. For all enzymes, amino acid residues surrounding the catalytic site are shown and numbered in grey, while for MAO-A and MAO-B, FAD cofactor is shown in green yellow. For SSAO, topaquinone and copper are shown in green and orange. Green: cocrystallized inhibitor (see Section 2). Yellow: cis-resveratrol. Orange: trans-resveratrol. Pink: pterostilbene. Purple: quercetin. Maroon: caffeic acid. π-π interactions are marked with light blue dotted lines, while H-bond interactions are marked with yellow dotted lines.