Modulation of Hydrogen Peroxide-Induced Oxidative Stress in Human Neuronal Cells by Thymoquinone-Rich Fraction and Thymoquinone via Transcriptomic Regulation of Antioxidant and Apoptotic Signaling Genes

Figure 7

GeXP multiplex gene expression analysis of apoptotic genes (AKT1, ERK, p38 MAPK, JNK, NF-κβ, and p53). Pretreatment with (a) Thymoquinone-rich fraction (TQRF) and (b) Thymoquinone (TQ), and subsequent exposure to 250 μM H₂O₂. Results are the mean ± SD. In each panel, mean values labeled with different alphabets are significantly different at .

(a)

(b)