From Six Gene Polymorphisms of the Antioxidant System, Only GPX Pro198Leu and GSTP1 Ile105Val Modulate the Risk of Acute Myeloid Leukemia

Table 5

Assessment of final model fit.

Performance measure	Final predictive model	Internal validation
Global measure of goodness of fit
Brier	0,17	0,18
(Nagelkerke)	0,13	0,10
Discrimination
AUC = stat (95% CI)	0,68 (0,63–0,75)	0,67
Somers’ index	0,36	0,34
Discrimination slope	1,00	0,90
Calibration
Hosmer-Lemeshow goodness-of-fit test (, value)	6,29 (0,39)
Unreliability index	−0,005	0,004
Quality index	0,09	0,06
Maximal error	<0,001	0,04
Mean squared error	0,00061	0,00057

Evaluated by bootstrapping method (number of resampling, ); the optimism corrected indices values.