Epistatic Interaction of CYP1A1 and COMT Polymorphisms in Cervical Cancer

Table 1

Distributions of CYP1A1 M1 (rs4646903) polymorphism in cervical cancer cases and controls.

CYP1A1; rs4646903	OR [95% CI]
	Controls	Cervical cancer		OR crude	OR adjusted
	TT	99 (79.8)						64 (61.0)	0.006	0.39 [0.22–0.71]	0.66 [0.27–1.66]	0.002	0.381
TC	23 (18.5)	36 (34.3)	2.29 [1.25–4.20]	1.25 [0.48–3.27]	0.007	0.655
CC	2 (1.6)	5 (4.8)	3.05 [0.58–16.06]	3.16 [0.33–30.22]	0.188	0.317
T	221 (89.0)	164 (78.0)	0.002	0.44 [0.26–0.73]	0.63 [0.29–1.39]	0.002	0.255
C	27 (11.0)	46 (22.0)		2.29 [1.37–3.85]	1.58 [0.72–3.48]	0.002	0.255

The values for the genotypes and respective allele frequencies represent absolute frequencies (relative frequencies, %). : test values; OR: odds ratio; : values for OR crude; : values adjusted for age (regression binary logistic); values statistically significant for value < 0.05.