Research Article
24-Week Exposure to Oxidized Tyrosine Induces Hepatic Fibrosis Involving Activation of the MAPK/TGF-β1 Signaling Pathway in Sprague-Dawley Rats Model
Table 3
Effects of O-Tyr on body weight (g), liver weight (g), and liver index (mg/g) (
).
| Parameters | Control | O-Tyr (2 g/kg) | O-Tyr (4 g/kg) | O-Tyr (8 g/kg) | Tyr (8 g/kg) |
| Initial body weight | 349.56 ± 10.24 | 345.13 ± 16.83 | 340.53 ± 10.46 | 351.67 ± 4.18 | 343.20 ± 8.35 | Final body weight | 734.98 ± 22.45 | 722.64 ± 26.68 | 637.18 ± 20.04 | 591.88 ± 13.34 | 728.96 ± 23.51 | Liver | 16.78 ± 0.83 | 16.63 ± 0.75 | 15.88 ± 0.88 | 17.09 ± 1.02 | 16.03 ± 1.10 | Liver index | 22.83 ± 0.48 | 23.01 ± 0.63 | 24.92 ± 0.77 | 28.87 ± 1.16 | 23.34 ± 0.84 |
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Notes: and versus rats in the control group, the same as Tables 4 and 5.
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