Efficiency of Base Excision Repair of Oxidative DNA Damage and Its Impact on the Risk of Colorectal Cancer in the Polish Population

Table 6

The distribution of genotypes and the analysis of the odds ratio (OR) for gene-gene interactions: 589Lys/Glu EXO1 and 780Arg/His LIG3 in patients with colorectal cancer (CRC) and the control group.

Genotype	Patients	Controls	OR (95% CI)
Lys/Lys-Arg/Arg	21	27	1 (ref.)	—
Lys/Lys-Arg/His	31	27	1.476 (0.684–3.185)	0.320
Lys/Lys-His/His	3	15	—	—
Lys/Glu-Arg/Arg	64	46	1.789 (0.902–3.547)	0.094
Lys/Glu-Arg/His	118	77	1.970 (1.041–3.731)	0.036
Lys/Glu-His/His	17	23	0.950 (0.407–2.218)	0.920
Glu/Glu-Arg/Arg	15	48	0.402 (0.178–0.906)	0.026
Glu/Glu-Arg/His	18	26	0.890 (0.389–2.038)	0.777
Glu/Glu-His/His	15	13	1.484 (0.582–3.784)	0.409