Oxidative Medicine and Cellular Longevity / 2016 / Article / Fig 2

Research Article

Lycopene Ameliorates Transplant Arteriosclerosis in Vascular Allograft Transplantation by Regulating the NO/cGMP Pathways and Rho-Associated Kinases Expression

Figure 2

Expression of ROCK1 and ROCK2 in each group. ((a1)–(a3) and (b1)–(b3)) Immunohistochemical staining of ROCK1 and ROCK2 in grafted arteries (original magnification ×200). ((a4) and (b4)) The mean of the IOD/area of ROCK1 and ROCK2 in each group. IOD/area: integrated optical density/area; the mean of the IOD/area of positive staining was used to accurately measure the degree of positive expression in immunohistochemical staining. for the isograft group compared with the allograft group; for the lycopene group compared with the allograft group. ((a5) and (b5)) Real-time quantitative PCR analysis of ROCK1 and ROCK2 mRNA expression in each group. and . ((a1) and (b1)) Isograft group; ((a2) and (b2)) allograft group; ((a3) and (b3)) lycopene group.

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