Review Article

The Role of the Reactive Oxygen Species and Oxidative Stress in the Pathomechanism of the Age-Related Ocular Diseases and Other Pathologies of the Anterior and Posterior Eye Segments in Adults

Figure 1

Schematic overview of the harmful influence of ROS and the oxidative stress on the trabecular meshwork structure and its function in glaucoma. ROS, reactive oxygen species; mtDNA, mitochondrial deoxyribonucleic acid; TM, trabecular meshwork; ECM, extracellular matrix; NF-κB, nuclear factor-κB; ROS/ONOO, reactive oxygen species/peroxynitrite; IOP, intraocular pressure.