Virus Infections on Prion Diseased Mice Exacerbate Inflammatory Microglial Response

Table 5

CA1 microglial numbers from lacunosum molecular cell layer from animals injected with normal brain homogenate (NBH) or NBH followed by Piry intranasal injection or with ME7 infected brain homogenate (ME7) or by ME7 followed by Piry virus intranasal injection.

Lacunosum molecular of CA1
Subjects		Thickness (μm)	CE (Scheaffer)
NBH
NBHVII-2	8326.01	34.4	0.06
NBHVII-3	5533.11	18.5	0.06
NBHVII-4	8070.49	19.8	0.05
Mean	7310	24.2	0.06
SD	1544
CV^2	0.045
CE^2	0.003
CE^2/CV^2	0.071
CVB^2	0.041
CVB^2 (% CV^2)	92.9
NBH+VIRUS
NBHV-3	8871	20.2	0.048
NBHVI-1	4969	15.6	0.059
NBHVI-2	4562	18.4	0.066
NBHVI-4	5784	19.3	0.058
Mean	6047	18.4	0.058
SD	1950
CV^2	0.104
CE^2	0.003
CE^2/CV^2	0.032
CVB^2	0.101
CVB^2 (% CV^2)	96.8
ME7
ME7IX-1	10399	24.5	0.05
ME7IX-4	8764	16.7	0.05
ME7X-2.	8281	21.3	0.06
ME7X-4	6176	23.9	0.07
Mean	8405	21.6	0.06
SD	1741
CV^2	0.043
CE^2	0.003
CE^2/CV^2	0.074
CVB^2	0.040
CVB^2 (% CV^2)	92.6
ME7+VIRUS
ME7VII-1	17412	22.9	0.04
ME7VII-4	10853	15.9	0.04
ME7VIII-1	15320	21.1	0.04
ME7VIII-4	9993	22.7	0.06
Mean	13395	20.7	0.05
SD	3553
CV^2	0.070
CE^2	0.002
CE^2/CV^2	0.031
CVB^2	0.068
CVB^2 (% CV^2)	96.9

CVB² = (CV, coefficient of variation; CE, Scheaffer coefficient of error; CVB, biological variation coefficient).